Only a block from the famous Zocalo (Park Principal), the Mision Hotel Merida is among the more convenient locations from which to enjoy a visit to the city. A guest of the hotel is only seconds from the Iglesias La Mejorada and the new Museum of Popular Art, and they will reach the Cathedral de San Ildefonso, Palacio Municipal (government houses), and the Lucas de Galvez Municipal Market in just a few minutes' walk. The Mision Hotel Merida is located at Calle 59 Numero 455 entre Calle 52 y Calle 54 Centro Historico and is 3 miles from the Manuel Crescencio Rejón International Airport.

Each guestroom in the Mision Hotel Merida is supplied with cable TV, high-speed Internet access, climate controls, a beverage station, a hair dryer, a minibar, and a large private bathroom.

Those staying at the Mision Hotel Merida will be able to rely on the many amenities which include 24-hour front desk service, meeting and conference rooms, an in-house restaurant, a tour desk, a lounge with bar service, a currency exchange, a modern fitness room, laundry and dry cleaning services, free parking on the premises, airport shuttles, a business service center, a concierge desk, a spa with massage and beauty treatments, and a swimming pool.